Case Studies #8 – The Simple Vitamin D3/K2/Magnesium Cure for Depression & The Vitamin D3 Case Study Search Engine

Case Studies #8 – The Simple Vitamin D3/K2/Magnesium Cure for Depression & The Vitamin D3 Case Study Search Engine

By Jeff T Bowles | Amazon Best Selling Science Author

Case Studies #8 – The Simple Vitamin D3/K2/Magnesium Cure for Depression


 The Vitamin D3 Case Study Search Engine


Depression/Anxiety disorders affect more than 40 million adults in the United States over the age of 18 costing $42 billion+ per year. And this doesn’t include kids! Most of the cost comes from victims buying very expensive drugs from Big Pharma that have all sorts of potential serious effects including suicide!

Being depressed is more than just feeling sad or moody from time to time. It is a serious mental disorder that affects a person’s physical and mental health. A person suffering from depression or anxiety disorders experiences distressing symptoms. These symptoms persist and interfere with the person’s everyday life.

Now what if I told you that it is likely that almost all of these disorders can be cured or at least minimized with Vitamin D3/K2 and magnesium supplementation for a cost of as little as $50 per year per person?

Notice the graph on the following page which shows that the closer one is to the equator, the lower the incidence of depression is as suggested by the amount of internet searches regarding depression from various locations on the globe. What does this suggest? That most if not all depression is caused by Vitamin D3 deficiency. It is likely not a random coincidence that the English language refers to happy people as having sunny personalities, while unhappy people are described as being gloomy. Why? Because the weather, by controlling how much Vitamin D3 one makes when the sun hits the skin, also ultimately controls many peoples’ moods.

A still popular treatment for SAD (seasonal affective disorder) where people become depressed in the fall/winter is to sit in front of a very bright light during the day time. The light is supposed to simulate the sun, but it doesn’t have any UV rays! If it did, the UV rays might cause you to make some Vitamin D3 which would help. As it is, light therapy is just a gimmick to sell lamps. In 1999, a study found that a single dose of 100,000 IU of Vitamin D3 was vastly superior to light therapy for depression. See-Glothet. al. J Nutr HealthAging 1999:3(1) 5-7.




The relationship between seasonality of Internet search trend of depression and geographic locations.

Comparisons are made between seasonal IMF of search trends, temperature and solar radiation. Each data point represents a geographic area and is categorized by its respective continent/land. For the coordinate of the data point, each geographic location’s latitude is the x-coordinate, and the y-coordinate is the cross-correlation coefficient between its seasonal IMF of local search trend and that of (a) temperature as well as (b) solar radiation. (From: Do Seasons Have an Influence on the Incidence of Depression? The Use of an Internet Search Engine Query Data as a Proxy of Human Affective Disorder. Albert C. Yang, Norden E. Huang, Chung-Kang Peng,Shih-Jen Tsai in PLOS.)

I recently created a high-dose Vitamin D3 Case Study Search Engine which you can use by going to the following URL>>

Just type in Depression and Search and you will get many many reports of how quickly Vitamin D3 has cured peoples’ depression. I find the following description particularly telling:

Great results from following the authors advice

By otter30 on December 14, 2012

Format: Kindle Edition|Verified Purchase

I was intrigued by the title but skeptical of the claims. However, the reasonable price swayed me. The book is written in the spirit of “The 4 Hour Body”. The author has come up with a very intriguing theory on how large doses of D3 could benefit us, and conducts an experiment on himself to verify aspects of the theory. He claims that he benefited greatly. Well, I took his advice and am now up to 35000 IU a day after 4 months. I can wholeheartedly say that the author’s advice has greatly benefited me. In addition to the resolution of general tiredness and overall joint pain/creakiness issues, an unexpected benefit was that I no longer take Prozac after being on it for over 18 years. I actually feel much better on the high D3 dose than I ever did from Prozac. I have to give the book 5 stars because of the good that comes from following the author’s advice. At this price, he is really doing a wonderful thing here.


Here are a few examples of what you will find with the search engine:


5.0 out of 5 stars

I like the book very much depression (German translation)

From manul On April 12, 2016

Format: Paperback|Verified purchase

I like the book a lot. You do not have to take these mega doses, but it reveals to you the importance of vitamin D3. I have even brought my vitamin D3 to about 70 and feel very good, all depressive moods have disappeared (female l 60)

5.0 out of 5 stars

I’m excited (German translation)

From Angelo Radner On February 11, 2016

Format: Paperback|Verified purchase

The book has opened my eyes and when you research something on the Internet, all the statements that are made in this book are correct. I am taking 10,000 drops daily in two drops and 1 tablet K2 daily. I’ve been fighting for 1 year with an extreme Crohn’s disease thrust. I could not eat anything without having extreme pain. For 4 days I have no more pain, no matter what I eat. I cannot believe it myself yet, but I am totally happy about it. Besides, I had depression and refused to take anti-depressants and lo and they are gone. I feel extremely fit and happy. The only side effect is that I sleep a bit worse, but that is in contrast to Crohn’s disease and the depression is nothing. I would recommend it to anyone. Just try it out. I was skeptical myself, but I have been taught a better one.

Follow ALL the Advice

By Music fan on September 3, 2013

Format: Kindle Edition

I enjoyed the author’s writing style — it is like talking to an enthusiastic friend. But anyone who wants to experiment with high doses of Vit D needs to also take the Vit K2! Don’t follow HALF the advice. My personal experience with daily 30,000 units of D3 (plus lots of K2): back pain disappeared; depression lessened considerably; energy increased considerably. My serum calcium FELL from a high-normal (but not optimal) 10.0 to a beautifully normal 9.2. My serum D levels are now on the high side of normal, up from a deficiency of below 30 ng/ml. My endocrinologist had advised me not to take extra Vit D in spite of my previous deficiency, because my serum calcium levels were not optimal (on the high side) and taking more Vit D, he said, would just raise my serum calcium levels. NOT!!! I am glad I took responsibility to educate myself about what my body needed. I now feel better than I have in years.

Thank you, Jeff, for sharing your experiment with the world.

5.0 out of 5 stars

RA sufferer very encouraged!

By Pam on May 31, 2015

Format: Kindle Edition|Verified Purchase

Read this informative book a few days ago and immediately increased the amount of D3 I have been taking and added K2. I was diagnosed with RA in April 2013. Rheumatologist put me on prednisone, hydroxychloroquine, methotrexate and an NSAID, all heavy duty drugs with serious side effects. I decided to discontinue the prescribed therapy against the advice of my doctor in February 2015. Well, I intend to heal. I was taking 5000 mg of D3 and have been upping it every day. I added K2, but I am not clear how much I should be taking. I am sleeping better and I feel good. Pain is minimal, no redness or swelling. Had a full blood panel recently and it looked good. D3 level was 30, the bottom of “normal”. Next testing scheduled for August. I will update progress then. RA causes fatigue and depression and honestly, I feel more energetic and happier already. I am very grateful for this book.

I came into this experiment/regimen with no real huge “health issues” but just a series of mental/physical issues I would love t

By anon1 on May 15, 2017

Format: Kindle Edition|Verified Purchase

I have had horrid insomnia and depression for the past few years. I hopped on this regimen and I have improved dramatically. Increased energy, mental clarity, and focus. So far, I am doing 30k of vitamin D3 and 1 super K2 in the morning, 1 capsule of magnesium at night. It works at waking me up. It also puts me in a better mood. I also notice my sleep improved quite a bit. I stay rested throughout the night and have more energy throughout the day. I plan on keeping up with it for a while. I would love to get some info of the dosages or dosage ranges that one would get if they sat in the sun all day. It’s been less than a week. It was hard getting out of bed just a few days ago. I will update in a month or so. For now, only experiencing benefits.

5.0 out of 5 stars

Thanks Jeff, this is revolutionary

By Inspector on 5 March 2017

Format: Kindle Edition|Verified Purchase

Too soon to see any concrete results but I generally feel much better in myself, after a week. Asthma, lower back pain, depression, arthritis, all seem to be less of a problem. A toe nail that I damaged months ago has come off. Is this a sign of repair starting? I’m taking 30,000 IU D3 and 1 mg (10 x 100mcg) of Mk7 K2 per day. I’m 70 in June 2017 and now feel some hope for my old age 😉 Rennie

5.0 out of 5 stars

This book really will change lives!

By angel emma on 26 December 2015

Format: Paperback|Verified Purchase

For about 3 or 4 years I had been experiencing some very strange symptoms in my health, some severe some very slight. The first ones I experienced were consistent tiredness and fatigue. I also experienced a mild to severe depression on and off. Again I thought this was down to other causes. After reading Jeff’s book I feel like I have stumbled upon a gold mine. Absolutely everything I have been experiencing for the past few years finally makes sense. I have been taking the 20,000 IU vitamin D for around 3 weeks now and started to run into a few problems sleeping at night, as I literally have too much energy now! I have since discovered that vitamin D should always be taken first thing in the morning as it temporarily blocks the production of melatonin which is the hormone that helps us get a good night’s sleep. I took it first thing yesterday and did seem a lot better last night so fingers crossed I’ve cracked it now 🙂

5.0 out of 5 stars

Very happy I stumbled upon this book

By Mitthraw Nuruodo on 19 December 2014

Format: Kindle Edition|Verified Purchase

I moved from sunnier country to UK and for the last 10 years I worked mainly nights and see very little sun for months so I started to feel really depressed about 6 years ago. At the time I took 2 bottles of Vitamin D3 but only 400IU, nevertheless I felt massive difference in my mood from deep depression to very happy bunny. It shocked me but after finishing them I forgot for another few years about it, until I stumbled upon this book. I bought myself a bottle of each, SuperK and Solgar10kIU and started from 10kIU/day for the first 3 days and then moved up to 20kIU as I wanted to move to healing part as soon as possible. It has only been two weeks so I can’t really say anything about the healing properties yet, although I noticed some positive effects I am getting from it now such as tremendous mood improvement and lots and lots of energy. I didn’t find any negatives so that’s good. I will post an update after few months about the results.

5.0 out of 5 stars

All Doctors should be made to read this invaluable book. – ALSO SEE ADDITION 7 MONTHS LATER

By maggie on 23 June 2013

Format: Kindle Edition|Verified Purchase

For the last year I have had unbearable arthritic pains resulting in swollen hands, fingers and wrists and pains in every joint and muscle. I could not sleep but was tired out all the time. I also have Crohn’s disease which I have managed with a diet for over 50 years. I live in the UK. Measurements are different in US. I thought that perhaps I didn’t need extra Vit D. I emailed Jeff who is extremely approachable and helpful and it appears that on the US scale my vitamin D levels were below even the reference range!! Immediately I started taking 4000 IU Vit D and also Vit K2. After 4 days I felt much better. On day 5 I took 12000 IU and the pain dramatically decreased. I upped the dose to 16000 and again the same. I am now on 20000 and I have never felt so well and have only been taking it for just over a week. My energy is slowly increasing. I feel the research of this man has saved me 7 MONTHS DOWN THE LINE. I have now been on Vit D3 & K2 for the last 7 months. My severe arthritis has disappeared and my Crohn’s disease is being cured. The depression I suffered from for years has gone. I feel better than I have done in my whole life. I only wish I had had Jeff Bowles book years ago.


A breath of fresh air! depression

By Purespirit7 on 26 February 2014

Format: Kindle Edition|Verified Purchase

This read is chock-full of information. I used to be taken in/brainwashed by mainstream medicine but with the help of people like Jeff T. Bowles I have cast off my rose-tinted glasses and taken responsibility for my own health and stopped blindly following advice peddled by the majority of doctors that are so indoctrinated by the system that they scoff and belittle all who question it! Thank you, Jeff for your passion and dedication.


Update 22/1/15 REMARKABLE RESULTS: My daughter is off anti-depressants. I feel so much better, physically, mentally and emotionally. My Mum feels so much better…less pain and has cut down on her medication. We have found the combination of D3/K2/Magnesium citrate a winning combination in three generations. This book kick started all this.


Now I want to add the two negative reviews and explain how and why they suggest these two reviewers had a negative effect from high-dose D3. It’s because they became or were likely magnesium deficient to begin with, and the high-dose Vitamin D3 caused or aggravated their deficiency. Problems like these can easily be avoided if one loads up on magnesium before undertaking a high-dose Vitamin D3 self-experiment and continues supplementing with magnesium on a daily basis while taking D3/K2. The magnesium deficiency can be aggravated in some cases immediately upon taking high-dose D3 as in the 1st case that follows or in other cases, it might take as long as 11 weeks as in the 2nd case that follows (for some people it might take years of high dose D3 to deplete one’s magnesium, it all depends on your initial status and daily magnesium intake):


This book RUINED my life!!!! Beware!!!

By Liz on September 20, 2014

Format: Paperback

Thanks to your idiotic book the last year of my life has been ruined. Vitamin D is not a vitamin. It’s a HORMONE!! Within a few days of taking 10,000IU of D a day with vitamin K (my note – should have been taking Vitamin K2) I became weak and fatigued. Lost my appetite. Had massive insomnia and suffered major anxiety and depression. Get D from the sun. Not synthetic pills. I should bill you for the thousands of dollars of doctors’ apps etc. trying to correct the mess of my life taking your advice has done.


Comment#1 –

Almost everyone who has a bad initial reaction to such a small amount of D3 10,000 IUs was magnesium deficient when starting – all your symptoms described are the same as magnesium deficiency! D3 uses up magnesium and can aggravate underlying magnesium deficiencies – too bad your doctors could not recognize that fact or you didn’t read the book carefully.


Comment #2 – 2 years ago

It is possible that by taking D3 the reviewer aggravated an underlying magnesium deficiency which can cause mental issues. It is also possible the reviewer obtained an improperly dosed batch of D3 as there have been mistakes in pills of D3 noted in the literature where 1,000 IU pills actually contained 1 million IU’s of D3…This can only be known through blood testing of D3 which apparently was not done. Taking 10,000 IU of D3 a day is tantamount to exposing one’s skin to the sun for about 10 minutes…hardly a dangerous undertaking.


5.0 out of 5 stars

Symptom Free of COPD in 10 Weeks

By Scott larson on March 25, 2014

I have been using the stuff for 11 weeks to date. I began with 20k IU and gradually moved up to 80K IU/day  by week 8. I began using the hormone for the treatment of COPD. I am 44 and have been battling symptoms for 11 years. I had seemingly run out of options. So trying this so called “extreme dose” felt like a last ditch effort. By week six I had noticeable improvement in breathing and congestion and asthma. I would say a 40 – 50% improvement. However, I no longer had stomach pain caused by eating grain. I went through a period of 10 days of severe pain in my hip and back (like the book said I would) and then was completely pain-free in these joints. At week 8 I had a 75 percent improvement in congestion, shortness of breath, asthma and coughing. And by week 10 I had NO symptoms of COPD!!!! In week 11 I backslid some. I have continued on with the 80k IU of the hormone and Vit K, but have had some MILD symptoms return. I have also experienced some irritability and depression (Note from JB – sounds like she finally induced a magnesium deficiency after the 11 months – these are some of symptoms).I plan to continue for at least six months while monitoring blood levels.



From JB-My take on this? Both of these reviewers described the mental issues that are often caused by magnesium deficiency. What are the symptoms? They include irritability, depression and anxiety amongst other things. You can do your own research about it on the internet if you want a full review. Here is one study I ran across:

Med Hypotheses 2006;67(2):362-70. Epub 2006 Mar 20.

Rapid recovery from major depression using magnesium treatment.

Eby GA1Eby KL.


As for Vitamin K2, one should always take Vitamin K2 with high-dose Vitamin D3. Why? Because it activates a protein your body needs to take calcium out of your blood and put it back in your bones. The only danger of high-dose Vitamin D3 is if you get too much calcium in your blood and it goes into your soft tissues.


There are also reports by a few that experienced anxiety and panic attacks taking high-dose D3 initially that taking K2 seemed to counteract the issues. But I have no explanation for how that might work as of yet.


So that’s it! If you ever suffer from depression why don’t you try high-dose D3/K2 and magnesium first before you call on Big Pharma’s drug salesmen (oops! I mean doctors). When it comes to depression you can try being your own doctor – but that’s up to you!

Jeff T Bowles: Being the author of the best-selling book on Vitamin D3 in the world, and given the topic of the book was the miraculous results of my one year experiment of taking HIGH DOSES of vitamin D3, puts me in the unique position of being the sounding board for many hundreds if not a few thousands of others who have embarked on their own high dose vitamin d3 experiment. Nobody on planet earth has this amount of unusual and exciting knowledge, and I will be sharing it with you in this series of 100 short articles describing a disease and some sort of amazing result achieved with high dose D3 therapy.

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